CGCG 480-022: A Distant Lonesome Merger?

Nuclear Receptors: Lonesome orphans

Nuclear receptors typically bind to DNA as homodimers or heterodimers, but increasing numbers of orphan receptors have been identified that bind DNA as monomers.

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Ischaemic stroke is the leading cause of severe long-term disability yet lacks drug therapies that promote the repair phase of recovery. This repair phase of stroke occurs days to months after stroke onset and involves brain remapping and plasticity within the peri-infarct zone. Elucidating mechanisms that promote this plasticity is critical for the development of new therapeutics with a broad ...

Bez nazwy-480

P03-022 - Calprotec in chronic nonbacterial osteomyelitis

Introduction The cytoplasmic S100 proteins derived from cells of myeloid origin. Calprotectin (MRP8/14 protein complex) might be a biomarker either for autoinflammation and autoimmunopathy. Since autoinflammatory diseases might be a diagnostic challenge calprotectin may be helpful in the diagnosis of autoinflammatory diseases. Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory, non...

New hopes for the lonesome pine

The star of last month's Chelsea Flower Show, also featuring in many other international events, was one of the world's rarest and most prehistoric trees, now the subject of innovative conservation strategies in its native Australia. Hannah Robertson reports. In a secret location deep within Wollemi National Park, 200 km northwest of Sydney, lives perhaps the most intriguing tree in the world: ...